Reacción #446708

Ecuación de reacción

2-aminobenzamide

4-methylbenzoyl isothiocyanate

→

desired product

Rendimiento 98.2%

N-[[[2-(Aminocarbonyl)phenyl]amino]thioxomethyl]-4-methylbenzamide

Rendimiento 98.2%

Disolventes

ether

ether

Condiciones de reacción

Tratamiento posterior

1. 1
   workup.ADDITIONwas added dropwise
2. 2
   Otrothe solid was collected

Procedimiento

To a stirred mixture of 5.4 g of 2-aminobenzamide and 200 ml of ether was added dropwise, a solution of 7.5 g of 4-methylbenzoyl isothiocyanate in 100 ml of ether over 30 minutes. After 48 hours, the solid was collected, giving 12.2 g of the desired product as grey crystals, mp 208°-210° C. (dec.).

Fuente