Reacción #441982

ord-f87f2cf901e847b9a89111e22ac49735

Ecuación de reacción

OC1CCN(c2nc(-c3ccccc3)nc3ccccc23)CC1
4-hydroxypiperidinyl-2-phenylquinazoline
[H-].[Na+]
sodium hydride
Fc1ccccc1
fluorobenzene
→
c1ccc(OC2CCN(c3nc(-c4ccccc4)nc4ccccc34)CC2)cc1
title compound
c1ccc(OC2CCN(c3nc(-c4ccccc4)nc4ccccc34)CC2)cc1
4-(4-Phenoxypiperidinyl)-2-phenylquinazoline

Reactantes

OC1CCN(c2nc(-c3ccccc3)nc3ccccc23)CC1
4-hydroxypiperidinyl-2-phenylquinazoline
[H-].[Na+]
sodium hydride
Fc1ccccc1
fluorobenzene

Reactivos

Ninguno

Disolventes

CN(C)C=O
dimethylformamide

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

Equimolar quantities of 4-(4-hydroxypiperidinyl-2-phenylquinazoline, sodium hydride, and fluorobenzene are heated in dimethylformamide to prepare the title compound.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US04377582uspto-grants-1983_03