Reacción #431447

ord-548afb166ae14a3aacdf4cdc7448af40

Ecuación de reacción

c1ccc2c(c1)OCO2
1,2-Methylenedioxybenzene
O=C(Cl)CCCCCBr
6-bromohexanoyl chloride
[Al+3].[Cl-].[Cl-].[Cl-]
aluminum chloride
O=C(CCCCCBr)c1ccc2c(c1)OCO2
6-bromo-1-(3,4-methylenedioxyphenyl)-1-hexanone
Rendimiento 43.5%

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    workup.ADDITIONtreated in the same manner as in Preparation Example 105

Procedimiento

1,2-Methylenedioxybenzene (1.18 g), 6-bromohexanoyl chloride (2.0 g) and aluminum chloride (1.31 g) were reacted and treated in the same manner as in Preparation Example 105 to give 1.22 g of 6-bromo-1-(3,4-methylenedioxyphenyl)-1-hexanone.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US05864039uspto-grants-1999_01