Reacción #430450

Ecuación de reacción

2-nitrobenzyl alcohol

octyl isocyanate

→

o-nitrobenzyl n-octylcarbamate

Rendimiento 62.1%

Disolventes

toluene

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturaheated
2. 2
   Temperaturaat reflux under nitrogen for 2 hours
3. 3
   Temperaturacooled
4. 4
   LavadoThe reaction solution was washed with water several times
5. 5
   Secadothe resulting toluene solution was then dried over sodium sulfate
6. 6
   FiltraciónThe sodium sulfate was filtered off
7. 7
   Otrothe solvent was removed from the filtrate on a rotary evaporator
8. 8
   OtroThe resulting solid was recrystallized twice from hexane

Procedimiento

100 mL toluene, 10 g 2-nitrobenzyl alcohol, and 11.4 g octyl isocyanate were placed in a 200-mL roundbottom flask, heated at reflux under nitrogen for 2 hours, and then cooled. The reaction solution was washed with water several times and the resulting toluene solution was then dried over sodium sulfate. The sodium sulfate was filtered off and the solvent was removed from the filtrate on a rotary evaporator. The resulting solid was recrystallized twice from hexane, yielding 12.5 g o-nitrobenzyl n-octylcarbamate as light yellow needle-like crystals.

Fuente