Reacción #42380

Ecuación de reacción

3-bromo-5-(hydroxymethyl)benzoic acid

trimethylsilyldiazomethane

→

title compound

Methyl 3-bromo-5-(hydroxymethyl)benzoate

Disolventes

methanol benzene

Condiciones de reacción

Tratamiento posterior

1. 1
   ConcentraciónThe reaction is concentrated under reduced pressure

Procedimiento

To 3-bromo-5-(hydroxymethyl)benzoic acid (7.0 g, 30 mmol) in 20% methanol/benzene (100 mL) is added trimethylsilyldiazomethane (2M in hexanes), and the reaction is stirred 16 h. The reaction is concentrated under reduced pressure to afford the title compound. ESI MS m/z 244.0 [M+H]+.

Fuente