Reacción #4215

Ecuación de reacción

N-[3-(Bromoacetyl)-2-oxo-1-imidazolidinyl]carbamic acid, 1,1-dimethylethyl ester

sodium iodide

→

title compound

N-[3-(iodoacetyl)-2-oxo-1-imidazolidinyl]carbamic acid, 1,1-dimethylethyl ester

Disolventes

acetone

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturaat reflux for three hours
2. 2
   Filtraciónfiltered hot through Celite
3. 3
   OtroThe solution was evaporated in vacuo

Procedimiento

N-[3-(Bromoacetyl)-2-oxo-1-imidazolidinyl]carbamic acid, 1,1-dimethylethyl ester (20.9 g, 65 mmol) was dissolved in acetone (250 ml) containing sodium iodide (10.5 g, 70 mmol). The solution was stirred at reflux for three hours and filtered hot through Celite. The solution was evaporated in vacuo to give the title compound as a light yellow solid, 23.9 g.

Fuente