Reacción #42045

Ecuación de reacción

1-(2-methyl-5-nitrophenyl)guanidine nitrate

sodium hydroxide

→

objective compound

Rendimiento 100.1%

1-(2-methyl-5-nitrophenyl)guanidine

Rendimiento 100.1%

Disolventes

Condiciones de reacción

Tratamiento posterior

1. 1
   FiltraciónThe crystals were filtered
2. 2
   Lavadosufficiently washed with water
3. 3
   Otroforced-air dried at 60° C.

Procedimiento

To 135 g of 1-(2-methyl-5-nitrophenyl)guanidine nitrate (Japanese Unexamined Patent Publication (Kokai) No. 6-87834), 21 g of sodium hydroxide in 1.0 L of a cold aqueous solution was directly added, followed by stirring at room temperature for 10 minutes. The crystals were filtered, sufficiently washed with water and then forced-air dried at 60° C. to obtain 102 g of the objective compound as pale yellow crystals.

Fuente