Reacción #41994

ord-cf1ee4e6db4a448696a3fcdc043f046f

Ecuación de reacción

CCC1(c2c[nH]c3c(N)cccc23)CCc2cc(F)ccc21
3-(1-ethyl-5-fluoro-indan-1-yl)-1H-indol-7-ylamine
O=S(=O)(Cl)c1ccccc1
benzenesulfonyl chloride
→
CCC1(c2c[nH]c3c(NS(=O)(=O)c4ccccc4)cccc23)CCc2cc(F)ccc21
title compound
CCC1(c2c[nH]c3c(NS(=O)(=O)c4ccccc4)cccc23)CCc2cc(F)ccc21
N-[3-(1-ethyl-5-fluoro-indan-1-yl)-1H-indol-7-yl]-benzenesulfonamide

Reactantes

CCC1(c2c[nH]c3c(N)cccc23)CCc2cc(F)ccc21
3-(1-ethyl-5-fluoro-indan-1-yl)-1H-indol-7-ylamine
O=S(=O)(Cl)c1ccccc1
benzenesulfonyl chloride

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

Utilizing 3-(1-ethyl-5-fluoro-indan-1-yl)-1H-indol-7-ylamine and benzenesulfonyl chloride, the title compound is prepared as in example 15. 0.21 g (33%). LC-MS m/z 295.1 (M++1).

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07728150B2uspto-grants-2010_06