Reacción #417926

Ecuación de reacción

sodium hydroxide

33

methyl 4-(undec-4Z-enyloxy)benzoate

→

white solid

Rendimiento 98.1%

4-(undec-4Z-enyloxy)benzoic acid

Rendimiento 98.1%

Disolventes

methanol

Condiciones de reacción

Tratamiento posterior

1. 1
   TemperaturaThe solution is refluxed for 20 hours
2. 2
   OtroAfter evaporating off the solvent
3. 3
   Extracciónextracted with DCM

Procedimiento

550 μL of 1 N sodium hydroxide solution (550 μmol) are added portionwise to 109 mg of 33 (358 μmol) in methanol (4 mL). The solution is refluxed for 20 hours. After evaporating off the solvent, the reaction medium is acidified with 0.5 N HCl and extracted with DCM. 102 mg of a white solid are obtained, i.e. a yield of 98%.

Fuente