Reacción #417919

Ecuación de reacción

PCC

alcohol

3-(undec-4Z-enyloxy)benzyl alcohol

→

yellow oil

Rendimiento 99.1%

3-(undec-4Z-enyloxy)benzaldehyde

Rendimiento 99.1%

Disolventes

DCM

Condiciones de reacción

Tratamiento posterior

1. 1
   Secadodried by coevaporation with toluene
2. 2
   TemperaturaThe reaction is heated to the reflux point of the DCM for 1 hour
3. 3
   TemperaturaAfter cooling
4. 4
   workup.ADDITIONthe reaction medium is diluted with ether
5. 5
   Filtraciónfiltered through Florisil
6. 6
   ConcentraciónAfter concentrating

Procedimiento

10 mL of anhydrous DCM and then 190 mg of PCC (881 μmol) are added under argon to 120 mg of alcohol 16 (434 μmol) dried by coevaporation with toluene. The reaction is heated to the reflux point of the DCM for 1 hour. After cooling, the reaction medium is diluted with ether and filtered through Florisil. After concentrating, 118 mg of a yellow oil are obtained, i.e. a yield of 99%.

Fuente