Reacción #41778

ord-423ac40369184f8fa67c4d931eed13e0

Disolventes

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    FiltraciónThe catalyst was filtered off
  2. 2
    Concentraciónthe solvent was concentrated

Procedimiento

A solution of {4-[2-methoxy-4-(methylamino)-5-nitrophenoxy](2-pyridyl)}-N-methylcarboxamide. In methanol was hydrogenated with 10% Pd/C. The catalyst was filtered off and the solvent was concentrated to yield {4-[3-amino-6-methoxy-4-(methylamino)phenoxy](2-pyridyl)}-N-methylcarboxamide. MS: MH+: 302.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07728010B2uspto-grants-2010_06