Reacción #41731

Ecuación de reacción

hydrochloric acid

2-amino-4-methoxyphenol

O-ethylxanthic acid

potassium

→

5-methoxybenzoxazole-2-thiol

Disolventes

pyridine

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturawas refluxed for two hours

Procedimiento

The mixture containing 2-amino-4-methoxyphenol (1 eq) and O-ethylxanthic acid, potassium salt (1.1 eq) in pyridine was refluxed for two hours. The resultant mixture was poured in to ice/water containing hydrochloric acid to yield a 5-methoxybenzoxazole-2-thiol as a tan solid. MS: MH+=182

Fuente