Reacción #412951

Ecuación de reacción

methyl 2,4-dibromobutyrate

Ethyl 2-cyano-3-phenylbutyrate

ethyl 2,4-dichlorbutyrate

methyl 2-cyano-3-phenylbutyrate

→

diethyl 2-phenyl-3-cyano-6-chlorohexane-3,4-dicarboxylate

Condiciones de reacción

Tratamiento posterior

1. 1
   Otrorespectively, in the alkylation reaction of Example 3

Procedimiento

Ethyl 2-cyano-3-phenylbutyrate and ethyl 2,4-dichlorbutyrate can be used in place of methyl 2-cyano-3-phenylbutyrate and methyl 2,4-dibromobutyrate, respectively, in the alkylation reaction of Example 3 to produce the corresponding diethyl 2-phenyl-3-cyano-6-chlorohexane-3,4-dicarboxylate. The latter product can then be reacted with the tricarboxylate of Example 4 and the dicarboxylate of Example 7 to give the corresponding pentaester and tetraester products.

Fuente