Reacción #409077

Ecuación de reacción

4′-(2-(4-propylphenyl)ethyl)-2′,3,5-trifluoro-4-iodobiphenyl

3-fluoro-4-iodo-(2-(4-propylphenyl)ethyl)benzene

dihydroxy(3,4-difluorophenyl)borane

→

2″,2′,6′,3,4-pentafluoro-4″-(2-(4-propylphenyl)ethyl)terphenyl

Condiciones de reacción

Tratamiento posterior

1. 1
   Otroobtained in the fifth step

Procedimiento

The same procedures as in the fourth step were repeated with the exception that 4.3 g (8.9 mmol) of the 4′-(2-(4-propylphenyl)ethyl)-2′,3,5-trifluoro-4-iodobiphenyl obtained in the fifth step was used in place of the 3-fluoro-4-iodo-(2-(4-propylphenyl)ethyl)benzene used in the fourth step, and that 2.1 g (13.3 mmol) of dihydroxy(3,4-difluorophenyl)borane was used in place of dihydroxy(3,5-difluorophenyl)borane, to obtain 3.4 g of a crude 2″,2′,6′,3,4-pentafluoro-4″-(2-(4-propylphenyl)ethyl)terphenyl. This product was recrystallized from mixed solvent of ethanol/ethyl acetate (8/2) to obtain 2.6 g of the subject compound. (Yield: 62.3%) Phase transition temperatures of this product were as follows:

Fuente