Reacción #4078

Ecuación de reacción

N-cyclohexyl-4-nitrosoaniline

NaOH

n-hexanol

→

N-cyclohexyl-p-phenylenediamine

Condiciones de reacción

Tratamiento posterior

1. 1
   Otroequipped with stirrer, condenser
2. 2
   Temperaturathermometer, and heated
3. 3
   TemperaturaHeating
4. 4
   Otroto rise to 115° C.
5. 5
   workup.ADDITIONdropped, within 10 minutes, to 100° C
6. 6
   TemperaturaWith the application of heat
7. 7
   Temperaturaa temperature of 90°-95° C. was maintained for 30 minutes

Procedimiento

51.0 g (0.25 mole) N-cyclohexyl-4-nitrosoaniline, 20.0 g (50%) NaOH and 135 g n-hexanol were charged to a 0.5 liter three-necked round bottom flask equipped with stirrer, condenser and thermometer, and heated while stirring to 95° C. until the development of an exotherm was observed. Heating was discontinued, the reaction temperature continued to rise to 115° C. and then dropped, within 10 minutes, to 100° C. With the application of heat, a temperature of 90°-95° C. was maintained for 30 minutes. The reaction mixture contained no unreacted nitroso compound. The yield of the product was 64 wt. %; m.p. 59°-61° C.

Fuente