Reacción #4071

Ecuación de reacción

methyl α-(2-methylphenyl)-β-methoxyacrylate

N-bromosuccinimide

succinimide

→

colorless crystals

Rendimiento 97.3%

Methyl α-(2-bromomethylphenyl)-β-methoxyacrylate

Rendimiento 97.3%

Disolventes

CCl4

Condiciones de reacción

Tratamiento posterior

1. 1
   FiltraciónThe mixture is filtered
2. 2
   Otrothe filtrate is evaporated down
3. 3
   workup.DISSOLUTIONthe oil which remains is dissolved in about 5 ml of acetone
4. 4
   Otrobrought to crystallization with n-hexane

Procedimiento

20.6 g of the methyl α-(2-methylphenyl)-β-methoxyacrylate obtained as described in method A, 17.65 g of N-bromosuccinimide, 0.2 g of azobisisobutyronitrile and 150 ml of CCl4 are slowly heated to 90° C. and kept at this temperature until all of the succinimide floats on the solvent. The mixture is filtered, the filtrate is evaporated down, and the oil which remains is dissolved in about 5 ml of acetone and brought to crystallization with n-hexane. 27.5 g of colorless crystals of melting point 86°-87° C. are obtained.

Fuente