Reacción #4069

Ecuación de reacción

N-bromosuccinimide

methyl phenylacetate

→

title compound

Rendimiento 93.1%

Methyl Bromo-Phenylacetate

Rendimiento 93.1%

Disolventes

carbon tetrachloride

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturato reflux
2. 2
   Temperaturarefluxed for about 12 hours
3. 3
   Filtraciónfiltered
4. 4
   ConcentraciónThe filtrate was concentrated by evaporation under vacuum

Procedimiento

In this example, a mixture containing 5.93 g of N-bromosuccinimide, 5.0 g of methyl phenylacetate; and a catalytic amount (about 0.1 g) of benzoyl peroxide in 50 ml of carbon tetrachloride was warmed to reflux and then refluxed for about 12 hours. The mixture was then cooled to about 0° C. and filtered. The filtrate was concentrated by evaporation under vacuum affording 7.1 g of the title compound as an oil.

Fuente