Reacción #4031

Ecuación de reacción

Methyl perfluorobutyrate

sodium trimethylsilanolate

→

sodium perfluorobutyrate

Rendimiento 84.0%

Disolventes

ether

Condiciones de reacción

Tratamiento posterior

1. 1
   FiltraciónThe solid was filtered under nitrogen
2. 2
   Lavadowashed with dry ether
3. 3
   Otrodried under a stream of nitrogen

Procedimiento

Methyl perfluorobutyrate (12.81 g, 56 mmol) was added dropwise to a stirred solution of sodium trimethylsilanolate (6.3 g, 56 mmol) in dry ether (300 mL) at room temperature under nitrogen. The reaction mixture was stirred overnight. The solid was filtered under nitrogen, washed with dry ether, and dried under a stream of nitrogen to afford sodium perfluorobutyrate (11.1 g, 84% yield) as a white solid: 19F NMR (D2O) δ -79.6 (t, J=8 Hz, CF3 --, 3F), -117.2 (q, J=8 Hz, CF3CF2CF2 --, 2F), -126.2 ppm (s, CF3CF2 --, 2F). Anal. Calcd. for C4F7NaO2 : C, 20.36; F, 56.35; Na, 9.74. Found: C, 20.84, 20.61, 20.58; F, 56.68, 53.24; Na, 9.89, 9.65.

Fuente