Reacción #3980

ord-e60e9f255ff64e7190309e64e3d68715

Ecuación de reacción

COc1cc(S(=O)(=O)Cl)ccc1-c1nc2c[nH][nH]c(=O)c-2n1
2-(2-methoxy-4-chlorosulfonyl-phenyl)-5-H-imidazo[4,5-d]pyridazin-4-one
CN
methylamine
→
CNS(=O)(=O)c1ccc(-c2nc3c[nH][nH]c(=O)c-3n2)c(OC)c1
2-(2-Methoxy-4-methylaminosulfonyl-phenyl)-5H-imidazo[4,5-d]pyridazin-4-one

Reactantes

COc1cc(S(=O)(=O)Cl)ccc1-c1nc2c[nH][nH]c(=O)c-2n1
2-(2-methoxy-4-chlorosulfonyl-phenyl)-5-H-imidazo[4,5-d]pyridazin-4-one
CN
methylamine

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

Prepared analogously to Example 11 from 2-(2-methoxy-4-chlorosulfonyl-phenyl)-5-H-imidazo[4,5-d]pyridazin-4-one and aqueous methylamine solution

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US04722929uspto-grants-1988_02