Reacción #3960

Ecuación de reacción

8-(2-dimethylamino-4-nitro-phenyl)purin-6-one

hydrogen

→

8-(4-Amino-2-dimethylamino-phenyl)-purin-6-one

Disolventes

methanol

Condiciones de reacción

Tratamiento posterior

1. 1
   FiltraciónAfter the catalyst has been subjected to suction filtration
2. 2
   Otrothe filtrate is evaporated to dryness in vacuo

Procedimiento

An amount of 0.9 gm of 8-(2-dimethylamino-4-nitro-phenyl)purin-6-one is hydrogenated in 50 ml of methanol in the presence of 0.5 gm of Raney nickel at ambient temperature and under 5 bars of pressure with hydrogen for three hours until the calculated quantity has been taken up. After the catalyst has been subjected to suction filtration, the filtrate is evaporated to dryness in vacuo.

Fuente