Reacción #3842

Ecuación de reacción

2-mercaptobenzophenone

diethyl azodicarboxylate

→

title compound

Rendimiento 50.7%

[2-(2-Benzoyl-phenyldisulfanyl)-phenyl]-phenyl-methanone

Rendimiento 50.7%

Disolventes

benzene

diethyl ether

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturarefluxed for 16 hours
2. 2
   TemperaturaThe solution was cooled
3. 3
   Concentraciónconcentrated in vacuo
4. 4
   Otroleaving a yellow liquid
5. 5
   OtroThe crude product was purified

Procedimiento

To a solution of 2-mercaptobenzophenone (2.3 g, 7.4 mmol) in diethyl ether (10 mL) was added dropwise diethyl azodicarboxylate (0.65 g, 3.7 mmol). The solution was stirred for 5 minutes at room temperature, then diluted with benzene (40 mL) and refluxed for 16 hours. The solution was cooled and concentrated in vacuo leaving a yellow liquid. The crude product was purified using silica gel chromatography (75% hexane/25% ethyl acetate) to give the title compound as a yellow foam (0.8 g, 50%);

Fuente