Reacción #367273

Ecuación de reacción

6-chloro-1-hexanol

mercaptoacetic acid

→

6-(Carboxymethylthio)-1-hexanol

Disolventes

NaOH

Condiciones de reacción

Tratamiento posterior

1. 1
   Extracciónextracted repeatedly with ethyl acetate
2. 2
   ConcentraciónThe combined extracts are concentrated to dryness
3. 3
   Otrothe residue purified by recrystallization

Procedimiento

4.5 ml (0.04M) of 6-chloro-1-hexanol is added to a solution of 2.8 ml (0.04M) of mercaptoacetic acid in 120 ml of 1N NaOH. The solution is warmed to about 50° C. for 16 hours, then acidified and extracted repeatedly with ethyl acetate. The combined extracts are concentrated to dryness and the residue purified by recrystallization.

Fuente