Reacción #3609

Ecuación de reacción

4-chloro-o-anisic acid

thionyl chloride

→

desired product

4-Chloro-2-methoxybenzoyl chloride

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturaat reflux for 1 hour
2. 2
   OtroThe volatiles are evaporated in vacuo
3. 3
   Otroto give a residue which
4. 4
   Concentraciónis concentrated from toluene three times
5. 5
   Otrodried under vacuum

Procedimiento

A solution of 2.0 g of 4-chloro-o-anisic acid in 22 ml of thionyl chloride is heated at reflux for 1 hour. The volatiles are evaporated in vacuo to give a residue which is concentrated from toluene three times and dried under vacuum to give 2.0 g of the desired product as a residue.

Fuente