Reacción #360843

Ecuación de reacción

HCl

2-Acetylfuran

dimethylamine hydrochloride

paraformaldehyde

→

crystals

Rendimiento 13.0%

N,N-dimethyl-2-(2-furoyl)ethylamine hydrochloride

Rendimiento 13.0%

Disolventes

ethanol

Condiciones de reacción

Tratamiento posterior

1. 1
   Otrowas pumped through the CMR (18 ml/min; 160°-70° C.; 500 kPa;)
2. 2
   Otrothe hot product collected in an ice-water cooled flask

Procedimiento

2-Acetylfuran (13.8 g), dimethylamine hydrochloride (13.3 g), paraformaldehyde (5.0 g) and ethanol (80 ml) acidified with concentrated HCl (1.0 ml) were stirred. Part of this mixture (27 ml) was pumped through the CMR (18 ml/min; 160°-70° C.; 500 kPa;) and the hot product collected in an ice-water cooled flask, to afford pale yellow crystals m.p. 172.5°-173° C. (cf lit.10 m.p. 173°-4° C.) in 13% yield.

Fuente