Reacción #355741

ord-f1d049b54ad24c3998e424ff8e9f1fcc

Ecuación de reacción

Cl.Cl.Nc1c(F)c(N)c(F)c(F)c1F
dihydrochloride
Cc1cc([N+](=O)[O-])ccc1NCCOCCO
2-[2-(4-nitro-2-methylphenylamino)ethoxy]ethanol
Cc1cc(N)ccc1NCCOCCO.Cl.Cl
amine
Cc1cc(N)ccc1NCCOCCO.Cl.Cl
2-[2-(4-amino-2-methylphenylamino)ethoxy]ethanol dihydrochloride

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

The 2-[2-(4-nitro-2-methylphenylamino)ethoxy]ethanol (13) obtained above was reduced with a boiling zinc/ammonium chloride/water/ethanol mixture. The corresponding amine was isolated in dihydrochloride form.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07445645B2uspto-grants-2008_11