Reacción #354964

Ecuación de reacción

oxazolidinone

3'-isopropyl-7-carbethoxyamino-3,4-dihydro-2H-1,5-benzodioxepin-3-spiro-5'-oxazolidin-2'-one

→

desired product

3-hydroxy-3-isopropylaminomethyl-7-carbethoxyamino-3,4-dihydro-2H-1,5-benzodioxepin

Disolventes

ethanol

Condiciones de reacción

Tratamiento posterior

1. 1
   Otroevaporated to a small volume
2. 2
   workup.ADDITIONdiluted with water
3. 3
   Extracciónextracted with ether
4. 4
   OtroThe dried etheral solution is evaporated

Procedimiento

This oxazolidinone from Step A above is refluxed in ethanol containing anhydrous hydrogen chloride. The solution is neutralized, evaporated to a small volume, diluted with water and extracted with ether. The dried etheral solution is evaporated to give the desired product.

Fuente