Reacción #354956

ord-1be76147e9bd4e39a51a1b1a9e1a1b39

Ecuación de reacción

CC(=O)OC1(CN(C(C)=O)C(C)C)COc2ccc([N+](=O)[O-])cc2OC1
3-acetoxy-3-(N-acetylisopropylaminomethyl)-7-nitro-3,4-dihydro-2H-1,5-benzodioxepin
[H][H]
hydrogen
→
CC(=O)OC1(CN(C(C)=O)C(C)C)COc2ccc(N)cc2OC1
3-acetoxy-3-(N-acetylisopropylaminomethyl)-7-amino-3,4-dihydro-2H-1,5-benzodioxepin

Reactantes

CC(=O)OC1(CN(C(C)=O)C(C)C)COc2ccc([N+](=O)[O-])cc2OC1
3-acetoxy-3-(N-acetylisopropylaminomethyl)-7-nitro-3,4-dihydro-2H-1,5-benzodioxepin
[H][H]
hydrogen

Reactivos

[Pt]
platinum

Disolventes

CCOC(C)=O
ethyl acetate

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

The 3-acetoxy-3-(N-acetylisopropylaminomethyl)-7-nitro-3,4-dihydro-2H-1,5-benzodioxepin when dissolved in ethyl acetate is reduced at low pressure over platinum with hydrogen to give 3-acetoxy-3-(N-acetylisopropylaminomethyl)-7-amino-3,4-dihydro-2H-1,5-benzodioxepin.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US03944560uspto-grants-1976_03