Reacción #350141

Ecuación de reacción

benzodioxolan

nitric acid

→

product

5-nitro-2-phenyl-1,3-benzodioxolan

Disolventes

Condiciones de reacción

Tratamiento posterior

1. 1
   Extracciónextracted several times with acetic ester
2. 2
   LavadoThe combined acetic ester phases were then washed several times with a solution of potassium bicarbonate
3. 3
   Otroby drying
4. 4
   Otroevaporation
5. 5
   Concentraciónby concentration
6. 6
   OtroCrystallization from ethanol

Procedimiento

A solution of 39.6 g (0.2 mol) of the benzodioxolan obtained as just described in 150 ml of acetic acid ester was added dropwise at 25° to 35° C. to 150 ml of a 33% nitric acid. The solution was poured into ice water after 2 hours and then extracted several times with acetic ester. The combined acetic ester phases were then washed several times with a solution of potassium bicarbonate and then with water, followed by drying and evaporation by concentration. Crystallization from ethanol furnished 37 g of a product of the melting point between 84° and 85° C.

Fuente