Reacción #348711

Ecuación de reacción

hydrochloric acid

2-ethyl-2-methyl-1-indanone

→

2-ethyl-2-methyl-indan

Disolventes

water

ethanol

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturaat reflux
2. 2
   workup.STIRRINGThe reaction mixture is subsequently stirred
3. 3
   Temperaturaat reflux for 28 hours
4. 4
   Temperaturacooled
5. 5
   Filtraciónfiltered
6. 6
   Lavadothe residue is washed with water/petroleum ether
7. 7
   ExtracciónThe filtrate is extracted with petroleum ether
8. 8
   Extracciónthe petroleum ether extract
9. 9
   Lavadois washed with water
10. 10
    Secadodried over sodium sulphate

Procedimiento

335 g of zinc dust and 33.5 g of mercury (II) acetate and a solution of 330 cc of concentrated hydrochloric acid in 280 cc of water are rapidly added dropwise in a stirring apparatus. The mixture is boiled at reflux and a solution of 63 g of 2-ethyl-2-methyl-1-indanone in 525 cc of ethanol is added dropwise within 10 minutes while stirring. The reaction mixture is subsequently stirred at reflux for 28 hours, cooled, filtered, and the residue is washed with water/petroleum ether. The filtrate is extracted with petroleum ether, the petroleum ether extract is washed with water and dried over sodium sulphate. The crude 2-ethyl-2-methyl-indan, obtained as an oil after evaporating the solvent, is purified by chromatography on aluminium oxide/petroleum ether.

Fuente