Reacción #344604

Ecuación de reacción

3-nitro-4-chloropyridine

ammonium acetate

ammonia

→

3-Nitro-4-aminopyridine

Rendimiento 59.0%

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturato cool
2. 2
   FiltraciónThe precipitated powder was collected by filtration
3. 3
   Otroto obtain 2.6 g of the intended yield: 59%)

Procedimiento

Five grams (31.5 mmol) of 3-nitro-4-chloropyridine was mixed with 26 g of ammonium acetate, and the mixture was heated at 130-140° C. for 3 hours. The mixture was allowed to cool, and then adjusted to pH 10 with concentrated aqueous ammonia. The precipitated powder was collected by filtration to obtain 2.6 g of the intended yield: 59%).

Fuente