Reacción #343292

Ecuación de reacción

5-ethyl-2-(4-isopropyl-4-methyl-5-oxo-2-imidazolidinyl)nicotinic acid

sodium hydroxide

→

sodium 5-ethyl-2-(4-isopropyl-4-methyl-5-oxo-2-imidazolidinyl)nicotinate

Disolventes

methanol

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe solvent is removed
2. 2
   Otroto give a solid which
3. 3
   Otrois dried in a vacuum oven at 60° C. for two days
4. 4
   Otrodarkens at 230° C.
5. 5
   Otrodecomposes at 247°-250° C.

Procedimiento

To 1.0 g 5-ethyl-2-(4-isopropyl-4-methyl-5-oxo-2-imidazolidinyl)nicotinic acid is added a solution of 0.1498 g sodium hydroxide in 20 mL absolute methanol. The mixture is stirred under nitrogen at room temperature overnight. The solvent is removed to give a solid which is dried in a vacuum oven at 60° C. for two days. The thus-formed sodium 5-ethyl-2-(4-isopropyl-4-methyl-5-oxo-2-imidazolidinyl)nicotinate darkens at 230° C. and decomposes at 247°-250° C.

Fuente