Reacción #342146

Ecuación de reacción

malononitrile

hydrazine hydrate

2-[(4-methylsulfanylphenyl)hydrazono]malononitrile

hydrazine hydrate

4-methylthioaniline

→

4-[(4-methylsulfanylphenyl)hydrazono]-4H-pyrazole-3,5-diamine

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroPrecipitate formed in the reaction tube
2. 2
   OtroThe resulting solid was isolated by filtration
3. 3
   Lavadowashed with ethanol
4. 4
   Otrodried

Procedimiento

4-[(4-methylsulfanylphenyl)hydrazono]-4H-pyrazole-3,5-diamine was prepared using 108 mg (0.5 mmol) of 2-[(4-methylsulfanylphenyl)hydrazono]malononitrile, which was derived from 4-methylthioaniline (117 mg, 1.0 mmol) and malononitrile (1.5 mmol), and hydrazine hydrate. Precipitate formed in the reaction tube immediately after the addition of hydrazine hydrate. The resulting solid was isolated by filtration, washed with ethanol, and dried to yield 95 mg (77%) of the compound as an orange solid.

Fuente