Reacción #341072

ord-e1791534d5dc4edab036da76d1587978

Ecuación de reacción

N#CSc1cnc(NC(=O)N(C2CCCCC2)C2CCCCC2)s1
1,1-dicyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-urea
O[C@H](CS)[C@@H](O)CS
dithioerythritol
CN(C)CCCCl
3-dimethylamino-1-propylchloride
→
CN(C)CCCSc1cnc(NC(=O)N(C2CCCCC2)C2CCCCC2)s1
1,1-Dicyclohexyl-3-[5-(3-dimethylamino-propylsulfanyl)-thiazol-2-yl]-urea

Reactantes

N#CSc1cnc(NC(=O)N(C2CCCCC2)C2CCCCC2)s1
1,1-dicyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-urea
O[C@H](CS)[C@@H](O)CS
dithioerythritol
CN(C)CCCCl
3-dimethylamino-1-propylchloride

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    OtroPrepared

Procedimiento

Prepared as described in general procedure (H) using 1,1-dicyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-urea, dithioerythritol and 3-dimethylamino-1-propylchloride.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07872139B2uspto-grants-2011_01