Reacción #341021

Ecuación de reacción

1,1-dicyclohexyl-3-(5-formyl-thiazol-2-yl)-urea

3-pyrazolidinone hydrochloride

sodium triacetoxyborohydride

→

desired product

Rendimiento 16.0%

1,1-Dicyclohexyl-3-[5-(3-oxo-pyrazolidin-1-ylmethyl)-thiazol-2-yl]-urea

Rendimiento 16.0%

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroPrepared

Procedimiento

Prepared as described in general procedure (P) using 1,1-dicyclohexyl-3-(5-formyl-thiazol-2-yl)-urea (42 mg. 0.125 mmol), 3-pyrazolidinone hydrochloride (23 mg, 0.188 mmol) and sodium triacetoxyborohydride (40 mg, 0.188 mmol) to afford 8 mg (16%) of the desired product after purification.

Fuente