Reacción #336642

ord-e358c11ee4ab4afeb9c488842b9140a4

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

The resolution is performed on 8-methoxy-2-(benzylamino)tetralin with the aid of (-)-di-p-toluoyltartaric acid according to Karlsson, et al., Acta Chem. Scand., B 42, 231-236 (1988). The enantiomers of 8-methoxy-2-(benzylamino)tetralin are debenzylated, yielding the corresponding enantiomers of 8-methoxy-2-aminotetralin, i.e., R-(+)- and S-(-)-8-methoxy-2-aminotetralin.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US05214156uspto-grants-1993_05