Reacción #335661

Ecuación de reacción

selenium dioxide

water

2-acetylfuran

→

α-oxo-2-furanacetaldehyde

Disolventes

dioxane

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturathe mixture was refluxed for 4 hours
2. 2
   Filtraciónfiltered
3. 3
   Otroevaporated
4. 4
   workup.DISSOLUTIONThe residue was dissolved in dichloromethane
5. 5
   workup.ADDITIONtreated with activated charcoal
6. 6
   Filtraciónfiltered
7. 7
   Otroevaporated
8. 8
   workup.DISTILLATIONThe residue was distilled

Procedimiento

A mixture of 55 g of selenium dioxide, 11 ml of water and 150 ml of dioxane was heated at 55° C. until solution was complete. A 55 g portion of 2-acetylfuran was added, the mixture was refluxed for 4 hours, then filtered and evaporated. The residue was dissolved in dichloromethane, treated with activated charcoal, filtered and evaporated. The residue was distilled, giving 28 g of α-oxo-2-furanacetaldehyde.

Fuente