Reacción #335025

Ecuación de reacción

acetyl chloride

N-[1-(benzyl)-4-piperidyl]-N-methylamine

triethylamine

→

N-Methyl-N-[1-(benzyl)-4-piperidyl]acetamide

Disolventes

methylene chloride

Condiciones de reacción

Tratamiento posterior

1. 1
   Otroevaporated
2. 2
   Lavadowashed with water
3. 3
   OtroAfter evaporation
4. 4
   Otrois obtained

Procedimiento

0.2 mole of acetyl chloride is slowly added to a solution containing 0.2 mole of N-[1-(benzyl)-4-piperidyl]-N-methylamine, 0.2 mole of triethylamine and 500 cm3 of methylene chloride. The mixture is left in contact for 2 hours, evaporated, taken up in ether and then washed with water. After evaporation, an oil which corresponds to the expected compound is obtained:

Fuente