Reacción #331110

ord-38a343cda898400b90eb4911b57fa02f

Ecuación de reacción

c1ccc2nc(N3CC4CNCC4C3)cnc2c1
Intermediate 35
c1ccc2nc(N3CC4CNCC4C3)cnc2c1
2-(Hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-quinoxaline
O=C(O)c1ccccc1Br
2-bromobenzoic acid
→
O=C(c1ccccc1Br)N1CC2CN(c3cnc4ccccc4n3)CC2C1
title compound
O=C(c1ccccc1Br)N1CC2CN(c3cnc4ccccc4n3)CC2C1
2-{5-[(2-Bromophenyl)carbonyl]hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}quinoxaline

Reactantes

c1ccc2nc(N3CC4CNCC4C3)cnc2c1
Intermediate 35
c1ccc2nc(N3CC4CNCC4C3)cnc2c1
2-(Hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-quinoxaline
O=C(O)c1ccccc1Br
2-bromobenzoic acid

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 35 and 2-bromobenzoic acid. MS (ESI) mass calcd. for C21H19BrN4O, 423.31; m/z found, 423.0, 425.0 [M+H]+.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US08653263B2uspto-grants-2014_02