Reacción #326167

Ecuación de reacción

2-trifluoromethyl-thiophene

chlorosulfonic acid

sulfonylchloride

→

5-trifluoromethyl-thiophene-2-sulfonylchloride

Disolventes

dichloromethane

Condiciones de reacción

Procedimiento

5-trifluoromethyl-thiophene-2-sulfonylchloride was prepared from commercially available 2-trifluoromethyl-thiophene through reaction with chlorosulfonic acid in dichloromethane and subsequent silica gel chromatography (1H-NMR of the sulfonylchloride (CDCl3, 400 MHz): δ [ppm] 7.9 (1H, d), 7.5 (1H, d)).

Fuente