Reacción #324243

ord-b8ba911d1c54415cb0f06ed5ce50c9ef

Ecuación de reacción

Cc1[nH]c(=S)[nH]c(=O)c1Cc1ccc(Cl)cc1
5-(4-Chlorobenzyl)-6-methyl-2-thiouracil
CI
methyl iodide
→
CSc1nc(C)c(Cc2ccc(Cl)cc2)c(=O)[nH]1
5-(4-chlorobenzyl)-6-methyl-2-methylthio-4-pyrimidone

Reactantes

Cc1[nH]c(=S)[nH]c(=O)c1Cc1ccc(Cl)cc1
5-(4-Chlorobenzyl)-6-methyl-2-thiouracil
CI
methyl iodide
—
Example 1 ( i )

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

5-(4-Chlorobenzyl)-6-methyl-2-thiouracil was methylated with methyl iodide as described in Example 1 (i) to give 5-(4-chlorobenzyl)-6-methyl-2-methylthio-4-pyrimidone (m.p. 248°-251°).

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US04159329uspto-grants-1979_06