Reacción #322786

Ecuación de reacción

2-butyryl-5-(1,4-dimethylnaphth-2-yl)-3-hydroxycyclohex-2-en-1-one

ethoxyamine hydrochloride

sodium acetate trihydrate

→

5-(1,4-dimethylnaphth-2-yl)-2-[1-(ethoxyimino)butyl]-3-hydroxycyclohex-2-en-1-one

Disolventes

ethanol

Condiciones de reacción

Tratamiento posterior

1. 1
   ExtracciónThe mixture was then immediately extracted with ether
2. 2
   SecadoThe dried (MgSO4)
3. 3
   Extracciónorganic extract
4. 4
   Otrowas evaporated

Procedimiento

A mixture of 2-butyryl-5-(1,4-dimethylnaphth-2-yl)-3-hydroxycyclohex-2-en-1-one (0.25 g), ethoxyamine hydrochloride (1.3 equiv) and sodium acetate trihydrate (1.3 equiv) were stirred in ethanol (30 ml) at room temperature for 4 hr. The mixture was then immediately extracted with ether. The dried (MgSO4) organic extract was evaporated to give 5-(1,4-dimethylnaphth-2-yl)-2-[1-(ethoxyimino)butyl]-3-hydroxycyclohex-2-en-1-one as a pale yellow oil. The product was characterized by proton nuclear magnetic resonance spectroscopy and the spectroscopic data is recorded in Table 4, Example 10.

Fuente