Reacción #319165

ord-6c338ea2cef04f129300214f89b16608

Ecuación de reacción

CC(C)(C)N
Tertiary butylamine
O=C(O)CNCP(=O)(O)O
N-phosphonomethylglycine
CC(C)(C)N(CC(=O)O)CP(=O)(O)O
N-t-butyl-N-phosphonomethylglycine
→
CC(C)(C)NCC(=O)O
N-t-butylglycine

Reactantes

—
esters
—
bromoacetate ester
CC(C)(C)N
Tertiary butylamine
O=C(O)CNCP(=O)(O)O
N-phosphonomethylglycine
CC(C)(C)N(CC(=O)O)CP(=O)(O)O
N-t-butyl-N-phosphonomethylglycine

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

Gaertner, U.S. Pat. No. 3,927,080, describes the production of N-phosphonomethylglycine by acid-catalyzed dealkylation of N-t-butyl-N-phosphonomethylglycine or its esters. Tertiary butylamine is reacted with a bromoacetate ester to produce an ester of N-t-butylglycine which is in turn reacted with formaldehyde and phosphorous acid to produce the N-t-butyl-N-phosphonomethylglycine precursor.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US04851131uspto-grants-1989_07