Reacción #319113

ord-bac90a4f387942999a8e79c5be428819

Ecuación de reacción

C1CCOC1
THF
O=C1CCC(c2ccccc2)CC1
4-phenylcyclohexanone
CCN(CC)CC
Et3N
C=C1CCC(c2ccccc2)CC1
4-phenyl-1-methylenecyclohexane
Rendimiento 10.0%

Reactivos

Ninguno

Disolventes

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

BDAM (2.83 grams) was suspended in 40 milliliters of toluene and 2.2 milliliters of THF were added dropwise. After 10 minutes of stirring, 2.10 grams of 4-phenylcyclohexanone were added. The reaction mixture was refluxed for 1 hour and hydrolyzed with hydrated Ca(OH)2 in the presence of Et3N. After the usual work up, 0.21 grams of 4-phenyl-1-methylenecyclohexane was isolated (10% yield).

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US04849574uspto-grants-1989_07