Reacción #318207

Ecuación de reacción

p-hydroxybenzoic acid

(R)-2-octanol

sulfuric acid

→

p-hydroxybenzoic acid 1-methylheptyl ester

Rendimiento 43.0%

Disolventes

benzene

Condiciones de reacción

Tratamiento posterior

1. 1
   Concentraciónconcentrated
2. 2
   Otropurified by column chromatography

Procedimiento

27.6 g of p-hydroxybenzoic acid and 39.0 g of (R)-2-octanol were refluxed for 10 hours in 300 ml of benzene in the presence of 0.5 ml of conc. sulfuric acid. Then, the reaction solution was cooled to the room temperature, and then concentrated and purified by column chromatography, to obtain 21.5 g of p-hydroxybenzoic acid 1-methylheptyl ester. (yield: 43%)

Fuente