Reacción #312221

Ecuación de reacción

hydroxylamine sulphate

sodium acetate trihydrate

acetic anhydride

2,6-dichlorobenzaldehyde

→

2,6-dichlorobenzonitrile

Rendimiento 84.0%

Disolventes

acetic acid

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturawas heated
2. 2
   Temperaturaat reflux for 34 hours
3. 3
   TemperaturaCooling
4. 4
   Filtraciónfiltration
5. 5
   Lavadowashing with water

Procedimiento

A mixture of 3.7 g of hydroxylamine sulphate, 7 g of sodium acetate trihydrate, 17 g of acetic anhydride, 5 ml of acetic acid and 4.5 g of 2,6-dichlorobenzaldehyde was heated at reflux for 34 hours. Cooling, filtration and washing with water gave 2.7 g of pure 2,6-dichlorobenzonitrile. Stripping of the filtrate gave an additional 1 gram of pure 2,6-dichlorobenzontirile thus producing an overall yield of 84%.

Fuente