Reacción #311652

Ecuación de reacción

Boron trifluoride

palmitic acid

2-methylhydroquinone

sodium acetate

→

2-methyl-5-hexadecanoylhydroquinone

Disolventes

methylene chloride

water

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturathe mixture was refluxed for another hour
2. 2
   OtroAfter 45 min the solution in methylene chloride was separated
3. 3
   Otroevaporated
4. 4
   Filtraciónfiltered with suction
5. 5
   Otrorecrystallized from n-chlorobutane

Procedimiento

Boron trifluoride was introduced with vigorous refluxing until saturation into a mixture of 27.2 g of palmitic acid, 13.7 g of 2-methylhydroquinone and 45 ml of methylene chloride. After standing overnight the mixture was refluxed for another hour and then decomposed with stirring in a solution of 25 g of sodium acetate in 220 ml of water. After 45 min the solution in methylene chloride was separated and evaporated. The residue was stirred with methanol, filtered with suction and recrystallized from n-chlorobutane.

Fuente