Reacción #3070

Ecuación de reacción

aldehyde

3-iodo-4-methylbenzaldehyde

n-BuLi

→

3-iodo-4-methylstyrene

Disolventes

THF

Condiciones de reacción

Tratamiento posterior

1. 1
   Extracciónprocessed by extraction and chromatography

Procedimiento

This aldehyde (1 mmol)was added to a premixed solution of 1.5 mmol of methyl triphenylphosphonium bromide and 1.2 mmol of n-BuLi in 5 mL of THF at 0° C. and this mixture was stirred for 3-6 h at rt and then processed by extraction and chromatography to give 3-iodo-4-methylstyrene.

Fuente