Reacción #3066

Ecuación de reacción

ethyl 3-bromo-4-methylbenzoate

NBS

benzoyl peroxide

→

ethyl 3-bromo-4-bromomethylbenzoate

Disolventes

CCl4

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturawas refluxed for 4 h
2. 2
   Filtraciónprocessed by filtration and chromatography

Procedimiento

A mixture of 1.0 mmol of ethyl 3-bromo-4-methylbenzoate, 1.0 mmol NBS, and 0.02 mmol benzoyl peroxide in 5 mL CCl4 was refluxed for 4 h and then processed by filtration and chromatography to provide ethyl 3-bromo-4-bromomethylbenzoate as an oil.

Fuente