Reacción #3013

Ecuación de reacción

2,6-dimethoxy-4-methylaniline

cyclohexanone

water

→

N-cyclohexylidene-2,6-dimethoxy-4-methylaniline

Disolventes

toluene

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturathe reaction mixture is heated
2. 2
   Temperaturaat reflux for 18 hours
3. 3
   Otrois removed as it
4. 4
   Otrois formed in the reaction mixture
5. 5
   OtroThe toluene is evaporated

Procedimiento

4.2 g of 2,6-dimethoxy-4-methylaniline are dissolved in 50 ml of toluene, 2.45 g of cyclohexanone are then added and the reaction mixture is heated at reflux for 18 hours. The water which is formed is removed as it is formed in the reaction mixture using a Dean and Stark apparatus. The toluene is evaporated and the oily N-cyclohexylidene-2,6-dimethoxy-4-methylaniline residue obtained is used without addition of purification in the following stage.

Fuente