Reacción #2925

ord-c6b8bc5eaf364257b6235f60aa86b148

Ecuación de reacción

Cc1nn(C)c(C)c1Br
4-Bromo-1,3,5-trimethylpyrazole
CC(=O)c1ccco1
2-acetylfuran
→
Cc1nn(C)c(C)c1C(C)(O)c1ccco1
1-(2-Furyl)-1-(1,3,5-trimethyl-4-pyrazolyl)ethanol

Reactantes

Cc1nn(C)c(C)c1Br
4-Bromo-1,3,5-trimethylpyrazole
—
4-lithio
CC(=O)c1ccco1
2-acetylfuran

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

4-Bromo-1,3,5-trimethylpyrazole was converted into the corresponding 4-lithio compound which was then reacted in situ with 2-acetylfuran.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US05731335uspto-grants-1998_03